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KMID : 1211620090040010001
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Journal of the Korean Society of Physical Medicine
2009 Volume.4 No. 1 p.1 ~ p.8
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Influences of Cold and Thermal Therapy on ILs and VEGF Expression after Muscle Contusion in Rats
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Heo Kwang-Ho
Bang Hyun-soo
Park Soo-Jin
Ahn Ji-hyun
Lee Hyun-min
Choen Song-hee
Kim Jin-Sang
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Abstract
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Purpose: The purpose of this study was to evaluate the effects of cold therapy and thermal therapy, and
immunoreactivity of vascular endothelial growth factor(VEGF), Interleukin-1(IL-1) and Interleukin-6(IL-6) on angiogenesis after muscle contusion injury.
Methods: Muscle contusion injury was induced in the gastronemius muscle by dropping a metal bead(22.8g).
Cold and thermal theraphy was applied immediately and directly to the skin of injured muscle daily for three days. (experimental group-1 5 cold pack, experimental group-2 50 hot pack, control group non applied,treatment time 10minutes)
Results: The experimental group-1 and 2 showed higher immunoreactivity of VEGF, IL-1, IL-6 than control group during 3 days(P<0.05). And the experimental group-2 showed higher than the experimental group-1 especially VEGF(P<0.05).
Conclusion: There data thermal therapy was more effective than cold therapy in the acute muscle contusion injury.
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KEYWORD
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Words Muscle contusion, Cold therapy, Thermal therapy, IL-1, IL-6, VEGF
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